The Role of Wnt Signalling in the Development of Somites and Neural Crest - Advances in Anatomy, Embryology and Cell Biology - Corina Schmidt - Books - Springer-Verlag Berlin and Heidelberg Gm - 9783540777267 - June 12, 2008
In case cover and title do not match, the title is correct

Corina Schmidt
The Role of Wnt Signalling in the Development of Somites and Neural Crest - Advances in Anatomy, Embryology and Cell Biology 2008 edition

Price
$ 105.49
excl. VAT

Ordered from remote warehouse

Expected to be ready for shipping Jul 16 - 22

Our customers say:

14-day return policy in accordance with European consumer protection law
Top ranking on Trustpilot
Add to your iMusic wish list

Not rated yet

1 Introduction 1. 1 Wnts and Development The f amily of Wnt genes consists of at least 19 members in vertebrates. Wnts ha v e multiple roles during normal development and aetiology of diseases (Wodarz and Nusse 1998; Moon et al. 2002, 2004). These genes encode for glycoproteins that are released in the intercellular space, acting as intercellular mediators (Moon et al. 1997). By binding to their special receptors, the Frizzled (Fz) receptors, they are able to activate at least three different pathways: the canonical, the non-canonical and the Ca 2+ pathway (Fig. 1 ). The Wnt family has been subdivided, using functional assays, into at least two subclasses. In Xenopus , Wnt1, Wnt3a and Wnt8 are able to induce axis duplication in embryos, whereas Wnt4, Wnt5a and Wnt11 cannot (Du et al. 1995). Those Wnts that are able to induce axis duplication are thought to act canonically; those who cannot are thought to act non-canonically. In the literature, therefore, some Wnts are called canonical Wnts while others are called n- cano nical Wnts, suggesting that a special Wnt always activates the same signalling pathway. It is unlikely that the specificity dictating cellular responses resides solely in the Wnt ligands because no one has reported sequence or structural motifs in Wnts that predict their activities in these cellular and embryonic assays.

64 pages, 15 colour illustrations

Media Books     Paperback Book   (Book with soft cover and glued back)
Released June 12, 2008
ISBN13 9783540777267
Publishers Springer-Verlag Berlin and Heidelberg Gm
Pages 64
Dimensions 155 × 235 × 5 mm   ·   158 g
Language English  

Mere med samme udgiver

See all of Corina Schmidt ( e.g. Paperback Book )