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Cardiovascular Pharmacogenetics - Handbook of Experimental Pharmacology M R Wilkins 2004 edition
Cardiovascular Pharmacogenetics - Handbook of Experimental Pharmacology
M R Wilkins
The Human Genome Project was sold to the general public largely on the basis that a complete picture of the structure of human DNA would lead to new and better medicines.
Marc Notes: Includes bibliographical references and index. Table of Contents: Preface.- The Role of Genotyping in Pharmacological Therapy.- Pharmacogenetics and the Treatment of Cardiovascular Disease.- Genetic Polymorphisms and Cardiovascular Drug Metabolism.- Genes that Modify Susceptibility to Atherosclerosis: Targets for Drug Action.- Lipid Lowering Responses Modified by Genetic Variation.- The Genetic Basis of Essential Hypertension and its Implications for Treatment.- Genetics Predisposition to Cardiac Hypertrophy.- Genetic Determinants of Susceptibility, Prognosis and Treatment in Heart Failure.- The Genetics of Cardiac Channelopathies: Implications for Therapeutics.- Insulin Resistance and Cardiovascular Disease - New Insights From Genetics.- Genetic Disruption of Nitric Oxide Synthases and Cardiovascular Disease - Lessons from a Candidate Gene.- Association of Thrombotic Disease with Genetic Polymorphism of Haemostatic Genes - Relevance to Pharmacogenetics.- Genetic Polymorphisms of Adhesion Molecules.- Genetic Regulation of Metalloproteinase Activity: Pathogenic and Therapeutic Implications.- Current Perspectives on Gene and Cell-based Therapies for Myocardial Protection, Rescue and Repair. Publisher Marketing: This volume intends to provide a panorama of our current understanding of the role of genetic information in the management of cardiovascular disease. A recurring plea from the contributors is the need for more hypothesis-driven, rigorously conducted and analysed clinical research. Perhaps this compilation of knowledge will provide a springboard for the design of informative clinical studies.
| Media | Books Hardcover Book (Book with hard spine and cover) |
| Released | December 2, 2003 |
| ISBN13 | 9783540402046 |
| Publishers | Springer-Verlag Berlin and Heidelberg Gm |
| Pages | 407 |
| Dimensions | 165 × 241 × 30 mm · 804 g |
| Language | German |
| Editor | Wilkins, Martin R. |
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