Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials - Springer Series in Pharmaceutical Statistics - Meinhard Kieser - Books - Springer Nature Switzerland AG - 9783030495275 - November 20, 2020
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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials - Springer Series in Pharmaceutical Statistics 2020 edition

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This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.


396 pages, 126 Illustrations, black and white; XIV, 396 p. 126 illus.

Media Books     Hardcover Book   (Book with hard spine and cover)
Released November 20, 2020
ISBN13 9783030495275
Publishers Springer Nature Switzerland AG
Pages 396
Dimensions 241 × 162 × 32 mm   ·   756 g
Language French  

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